HRID2081137

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：CC[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)C1CC1

HCID70324238

未命名化合物

PRODUCTS

产物

反应SMILES：CC[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)C1CC1

HCID53465517

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID313

Hydrochloric Acid

ClH

溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

Tert-butyl (1R,2R)-1-(cyclopropylsulfonylcarbamoyl)-2-ethylcyclopropylcarbamate (0.53 g, 1.60 mmol) was dissolved in 4 N HCl in dioxane (20 mL) and stirred at rt for 5 hour. Removal of solvent gave (1R,2R)-1-amino-N-(cyclopropylsulfonyl)-2-ethylcyclopropanecarboxamide dihydrchloride as a white foamy solid. It was used directly in the next step without further purification.

WORKUP

后处理

customRemoval of solvent