反应详情

A mixture of 1-bromo-4-methylaminoanthraquinone (16 parts) of the following formula: ##STR10## and m-chloroacetoanilide (12.7 parts) of the following formula: ##STR11## was heated at 135°-145° C. for 25 hours in o-dichlorobenzene in the presence of metallic copper (powder, 0.3 part) and potassium carbonate (17.3 parts). After cooling, the resulting precipitate was filtrated, washed with methanol and then water and dried to obtain a cake (13.5 parts, yield 70%) of anthrapyridone compound of the following formula: This compound showed a single red spot when thin-layer-chromatographed and λ max (in N,N-dimethylformamide) of 547 nm and had a melting point of 281°-284° C. (uncorrected).

1. temperatureAfter cooling
2. filtrationthe resulting precipitate was filtrated
3. washwashed with methanol
4. dry with materialwater and dried