HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-(2-Iodophenoxy)-butyric acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(2-Iodophenoxy)butyric acid ethyl ester | HCID 15070115 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(2-Iodophenoxy)-butyric acid methyl ester | HCID 43479543 | 93.9% |
Reaction Steps
Under the conditions of example 5A, 1 g of 4-(2-iodophenoxy)-butyric acid ethyl ester in 10 ml of methanol and 10 ml of 1 n sodium hydroxide solution is saponified, worked up, and 900 mg of 4-(2-iodophenoxy)-butyric acid methyl ester with a melting point of 66.5°-67° C. is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05183925 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-cd803c16a9024af0bc3cc197f1df89d5 |
| Source note | uspto-grants-1993_02 |