Methyl p-toluenesulfonate → HCID 15052270, compound

HRID 2081511Notes

Reaction equation

HRID 2081511 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:4]([CH2:14][OH:15])[CH2:3]1.[C:16]1([CH3:27])[CH:21]=[CH:20][C:19]([S:22]([O:25]C)(=[O:24])=[O:23])=[CH:18][CH:17]=1>>[C:16]1([CH3:27])[CH:17]=[CH:18][C:19]([S:22]([O-:25])(=[O:23])=[O:24])=[CH:20][CH:21]=1.[CH3:1][N+:2]1([CH3:16])[CH2:7][CH2:6][CH:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:4]([CH2:14][OH:15])[CH2:3]1

Participants

3

Reactant 2

HCID 6645Methyl p-toluenesulfonateHCID 11275751HCID 11275751, compound

Product 1

HCID 15052270HCID 15052270, compoundYield 94.1%

Procedure

The procedures of Reference Example 10 were repeated using 1.0 g of 1-methyl-4-phenyl-3-piperidinemethanol and 910 mg of methyl p-toluenesulfonate to give 900 mg of the desired compound.

Sources & evidence

ORD record
ord-03ef5a3ec7f84d14b52a582b477da1d6
Source dataset
uspto-grants-1993_02
Patent number
US05183811

Reaction notes

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