2-Methylpiperazine → HCID 67883376, compound

HRID 2081566Notes

Reaction equation

HRID 2081566 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9]3=[C:10]([CH2:13][C@H:14]([CH3:15])[N:8]3[CH:7]=[C:6]([C:16]([OH:18])=[O:17])[C:5]2=[O:19])[C:11]=1Cl.[CH3:20][CH:21]1[CH2:26][NH:25][CH2:24][CH2:23][NH:22]1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:9]3=[C:10]([CH2:13][C@H:14]([CH3:15])[N:8]3[CH:7]=[C:6]([C:16]([OH:18])=[O:17])[C:5]2=[O:19])[C:11]=1[N:25]1[CH2:24][CH2:23][NH:22][CH:21]([CH3:20])[CH2:26]1

Participants

3

Reactant 2

HCID 660572-MethylpiperazineHCID 18649755HCID 18649755, compound

Product 1

HCID 67883376HCID 67883376, compound

Procedure

(+)-8,9-dichloro-2-(S)-methyl-6-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid obtained in Example 6 and 2-methylpiperazine were used as the starting substances, and treated in a manner analogous to Example 8, to give the title compound.

Workup

  1. additiontreated in a manner analogous to Example 8

Sources & evidence

ORD record
ord-8ec913ae1af14bd2baf0cd3c76f0592e
Source dataset
uspto-grants-1993_02
Patent number
US05185337

Reaction notes

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