Ammonium Chloride → HCID 19780253, compound

HRID 2081580Notes

Reaction equation

HRID 2081580 reaction equation
[CH2:1]([C:8]1[N:13]=[C:12]([C:14](=[NH:17])OC)[CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl-:18].[NH4+:19]>C(O)C>[ClH:18].[CH2:1]([C:8]1[N:13]=[C:12]([C:14]([NH2:17])=[NH:19])[CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 53840049Methyl 6-(phenylmethyl)-2-pyridinecarboximidate

Product 1

HCID 19780253HCID 19780253, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of methyl 6-benzyl-2-picoline imidate (0.81 g, 0.0036 moles) and ammonium chloride (0.21 g, 0.0039 moles) in ethanol (9 ml) was refluxed for 5 hours. The ethanol was removed in vacuo to give 6-benzyl-2-picoline amidine hydrochloride which was used in the final stage without further purification.

Workup

  1. temperaturewas refluxed for 5 hours
  2. customThe ethanol was removed in vacuo

Sources & evidence

ORD record
ord-cbbe57ffb2994fe0adf991e5ff8a72d5
Source dataset
uspto-grants-1993_02
Patent number
US05185339

Reaction notes

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