5-Octyldihydrofuran-2(3H)-one → HCID 10363695, compound

HRID 2081618Notes

Reaction equation

HRID 2081618 reaction equation
[C:1]1(=[O:14])[O:13][CH:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:3][CH2:2]1.[CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:26])[CH3:25])[C:19]=1[N:27]=[C:28]=[O:29])([CH3:17])[CH3:16].C([N-]C(C)C)(C)C.[Li+]>>[CH3:17][CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:25])[CH3:26])[C:19]=1[NH:27][C:28]([CH:2]1[CH2:3][CH2:4][CH:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[O:13][C:1]1=[O:14])=[O:29])[CH3:16]

Participants

4

Reactant 3

HCID 168215-Octyldihydrofuran-2(3H)-oneHCID 922592,6-Diisopropylphenyl isocyanateHCID 2724682Lithium diisopropylamide

Product 1

HCID 10363695HCID 10363695, compound

Procedure

The title compound was prepared from (±)-δ-dodecanolactone (5.0 g, 0.025 mol), 2,6-diisopropylphenyl isocyanate (5.12 g, 0.025 mol), and lithium diisopropylamide (0.025 mol) using the procedure described in Example 1.

Sources & evidence

ORD record
ord-0d01646daa2d4309a0b3c8f671cc859c
Source dataset
uspto-grants-1993_02
Patent number
US05185349

Reaction notes

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