HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2-[(4-Acetamidophenyl)methylene]-1,3-dicyclopropyl-1,3-propanedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Acetamidobenzaldehyde | HCID 73942 | — |
| Reactant | 1,3-Dicyclopropylpropane-1,3-dione | HCID 13780782 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-[(4-Acetamidophenyl)methylene]-1,3-dicyclopropyl-1,3-propanedione | HCID 19096394 | — |
Reaction Steps
A mixture containing 1.6 g 4-acetamidobenzaldehyde, 1.5 g 1,3-dicyclopropyl-1,3-propanedione, 0.2 ml of piperidine and 0.4 ml of acetic acid in 50 ml of toluene was refluxed for 3 h by using a Dean-Stark separator. After standing over night at room temperature the crystals were filtered and washed with toluene. The product was recrystallized from ethanol. Yield 2.0 g, mp 166°-167° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05185370 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-944f399ec8e24c50937834f23f13c95d |
| Source note | uspto-grants-1993_02 |