反应详情

A mixture containing 1.6 g 4-acetamidobenzaldehyde, 1.5 g 1,3-dicyclopropyl-1,3-propanedione, 0.2 ml of piperidine and 0.4 ml of acetic acid in 50 ml of toluene was refluxed for 3 h by using a Dean-Stark separator. After standing over night at room temperature the crystals were filtered and washed with toluene. The product was recrystallized from ethanol. Yield 2.0 g, mp 166°-167° C.

1. temperaturewas refluxed for 3 h
2. waitAfter standing over night at room temperature
3. filtrationthe crystals were filtered
4. washwashed with toluene
5. customThe product was recrystallized from ethanol