HRID2081878

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID140766

4-(2-Thienyl)butanoic acid methyl ester

C9H12O2S

HCID573592

1-Methyl-1H-imidazole-5-carbaldehyde

C5H6N2O

HCID3704115

未命名化合物

$结构：CCCCc1ncc(/C=C(\Cc2cccs2)C(=O)O)n1Cc1ccccc1Cl$

HCID10047444

未命名化合物

HCID10107530

1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

C15H17ClN2O

PRODUCTS

生成物

$结构：CCCCc1ncc(/C=C(\CCc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1$

HCID14952960

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure of Example 20 replacing methyl 3-(4-pyridyl)propanoate with methyl 4-(2-thienyl)butanoate and 2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde with 2-n-butyl-1-)4-carbomethoxyphenyl)methyl-1H-imidazol-5-carboxaldehyde; mp 244°-246° C. (d).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-be4cd52926ba466fbc598ef1afc1077c
来源数据集: uspto-grants-1993_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05185351
来源说明: uspto-grants-1993_02

反应 SMILES

N1C=CC(CC[C:9]([O:11]C)=[O:10])=CC=1.[S:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[CH2:18][CH2:19][CH2:20][C:21]([O:23]C)=[O:22].[CH2:25]([C:29]1[N:30]([CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=2Cl)[C:31]([CH:34]=O)=[CH:32][N:33]=1)[CH2:26][CH2:27][CH3:28].CN1C(C=O)=CN=C1.C(C1N(CC2C=CC=CC=2Cl)C(/C=C(\CC2SC=CC=2)/C(O)=O)=CN=1)CCC>>[CH2:25]([C:29]1[N:30]([CH2:36][C:37]2[CH:42]=[CH:41][C:40]([C:9]([OH:11])=[O:10])=[CH:39][CH:38]=2)[C:31](/[CH:34]=[C:20](\[CH2:19][CH2:18][C:14]2[S:13][CH:17]=[CH:16][CH:15]=2)/[C:21]([OH:23])=[O:22])=[CH:32][N:33]=1)[CH2:26][CH2:27][CH3:28]