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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 208203Generated: October 30, 2026

2-Bromo-5-((tert-butoxycarbonyl)amino)thiazole-4-carboxylic acid → tert-butyl 2-bromo-4-(1-(2,2-difluoroethyl)-5-(4-hydroxyazepan-1-yl)-1H-pyrazol-4-ylcarbamoyl)thiazol-5-ylcarbamate

https://huagongshe.com/reaction/208203

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-((tert-butoxycarbonyl)amino)thiazole-4-carboxylic acidHCID 58182156—
Reactant1-(4-amino-1-(2,2-difluoroethyl)-1H-pyrazol-5-yl)azepan-4-olHCID 86679970—
Producttert-butyl 2-bromo-4-(1-(2,2-difluoroethyl)-5-(4-hydroxyazepan-1-yl)-1H-pyrazol-4-ylcarbamoyl)thiazol-5-ylcarbamateHCID 86679969—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6fea4bc3565a4367873516e964e1f1fc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)