Azido(trimethyl)stannane → HCID 178441892, compound

HRID 2082057Notes

Reaction equation

[CH2:1]([C:5]1[N:6]([CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=3[C:32]#[N:33])=[CH:22][CH:21]=2)[C:7]2[N:8]([CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4].C[Sn]([N:38]=[N+:39]=[N-:40])(C)C>>[CH2:1]([C:5]1[N:6]([CH2:19][C:20]2[CH:21]=[CH:22][C:23]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=3[C:32]3[NH:40][N:39]=[N:38][N:33]=3)=[CH:24][CH:25]=2)[C:7]2[N:8]([CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 5104973Azido(trimethyl)stannane

HCID 10320552HCID 10320552, compound

Product 1

HCID 178441892HCID 178441892, compoundYield 44%

Procedure

Reaction of 2-butyl-3-[(2'-cyanobiphenyl-4-yl)methyl]-5-phenyl-3H-imidazo[1,2-b][1,2,4]triazole (from Step B and C) with trimethyltin azide according to the procedure of Example 1, Step G, gave a 44% yield of the title compound as a light tan solid, mp >160° C. (gradual); homogeneous by TLC in 90:10:0.1 CH2Cl2 -MeOH-AcOH.

Sources & evidence

ORD record: ord-6d56119453e346afaec8a03f9aedebf1
Source dataset: uspto-grants-1993_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05187179

Reaction notes

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