Azido(trimethyl)stannane → HCID 178441898, compound

HRID 2082059Notes

Reaction equation

HRID 2082059 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[C:27]#[N:28])=[CH:17][CH:16]=2)[C:7]2[N:8]([CH:10]=[C:11]([CH3:13])[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4].C[Sn]([N:33]=[N+:34]=[N-:35])(C)C>>[CH2:1]([C:5]1[N:6]([CH2:14][C:15]2[CH:16]=[CH:17][C:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[C:27]3[NH:35][N:34]=[N:33][N:28]=3)=[CH:19][CH:20]=2)[C:7]2[N:8]([CH:10]=[C:11]([CH3:13])[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 5104973Azido(trimethyl)stannaneHCID 11726588HCID 11726588, compound

Product 1

HCID 178441898HCID 178441898, compoundYield 31%

Procedure

Reaction of 2-butyl-3-[(2'-cyanobiphenyl-4-yl)methyl]-5-methyl-3H-imidazo[1,2-b][1,2,4]triazole (from Steps B and C) with trimethyltin azide according to the procedure of Example 1, Step G, gave a 31% yield of the title compound as a light brown solid, mp 124°-125° C.; homogeneous by TLC in 90:10:0.1 CH2Cl2 -MeOH-AcOH.

Sources & evidence

ORD record
ord-04d60ac544564155ba30009ef276b919
Source dataset
uspto-grants-1993_02
Patent number
US05187179

Reaction notes

Loading…