Azido(trimethyl)stannane → HCID 178441890, compound

HRID 2082065Notes

Reaction equation

HRID 2082065 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:20][C:21]2[CH:26]=[CH:25][C:24]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=3[C:33]#[N:34])=[CH:23][CH:22]=2)[C:7]2[N:8]([C:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[C:11]([CH3:13])[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4].C[Sn]([N:39]=[N+:40]=[N-:41])(C)C>>[CH2:1]([C:5]1[N:6]([CH2:20][C:21]2[CH:22]=[CH:23][C:24]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=3[C:33]3[NH:41][N:40]=[N:39][N:34]=3)=[CH:25][CH:26]=2)[C:7]2[N:8]([C:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[C:11]([CH3:13])[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 5104973Azido(trimethyl)stannaneHCID 10026552HCID 10026552, compound

Product 1

HCID 178441890HCID 178441890, compoundYield 32%

Procedure

Following the procedure of Example 1, Step G, 2-butyl-3-[(2'-cyanobiphenyl-4-yl)methyl]-5-methyl-6-phenyl-3H-imidazo[1,2-b][1,2,4]triazole (from Step B) was reacted with trimethyltin azide to give a 32% yield of the title compound as a brown solid, mp>108° C. (gradual); homogeneous by TLC in 90:10:0.1 CH2Cl2 -MeOH-AcOH.

Sources & evidence

ORD record
ord-8ff4485264eb4716acd0d0a6a119c17b
Source dataset
uspto-grants-1993_02
Patent number
US05187179

Reaction notes

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