HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → HCID 12674277, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 3631156 | HCID 3631156 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12674277 | HCID 12674277 | — |
Reaction Steps
0.04 mol of ethyl 1-(5-phenyl-2-pyrimidinyl)-4-piperazinecarboxylate are boiled under reflux with 0.78 mol of KOH in 400 ml of C2H5OH and 40 ml of H2O under N2 protective gas for 15 hours. The mixture is evaporated to dryness, water is added and the residue is taken up in CH2Cl2. After washing with water, the organic phase is separated off and evaporated to dryness, whereupon the amine is obtained as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05187276 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-395522a75b634041b750ac3d7d6c648a |
| Source note | uspto-grants-1993_02 |