Sodium Methoxide → HCID 67783632, compound

Participants

Reaction Steps

8.4 g (0.047 mol) of 30% strength sodium methylate were added to a mixture of 10 g (0.047 mol) of 2-amino-4-chlorodifluoromethoxy-6-fluoro-1,3,5-triazine in 100 ml of methanol at 0° C. in the course of 15 minutes, while stirring. Stirring was carried out for one hour at 0° C., after which the mixture was evaporated down under reduced pressure, the residue was taken up in methylene chloride and the solution was extracted with water. Drying and evaporation gave 10.4 g (98.5% of theory) of the title compound of melting point 109°-111° C.

Provenance & Evidence