反应详情

Thionyl chloride (1.6 ml) was added to a solution of 2-(4-fluorobenzoyl)benzoic acid (3.6 g) and pyridine (0.03 ml) in benzene (40 ml), followed by refluxing for an hour. The solvent was distilled off to give 2-(4-fluorobenzoyl) benzoyl chloride (IRνmaxNujol : 1790 cm-1).

1. temperatureby refluxing for an hour
2. distillationThe solvent was distilled off