Pyridine → HCID 53651119, compound

HRID 2082337Notes

Reaction equation

HRID 2082337 reaction equation
S(Cl)([Cl:3])=O.[F:5][C:6]1[CH:22]=[CH:21][C:9]([C:10]([C:12]2[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=2[C:14](O)=[O:15])=[O:11])=[CH:8][CH:7]=1.N1C=CC=CC=1>C1C=CC=CC=1>[F:5][C:6]1[CH:22]=[CH:21][C:9]([C:10]([C:12]2[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=2[C:14]([Cl:3])=[O:15])=[O:11])=[CH:8][CH:7]=1

Participants

5

Reactant 3

HCID 1049PyridineHCID 24386Thionyl ChlorideHCID 820992-(4-Fluorobenzoyl)benzoic acid

Product 1

HCID 53651119HCID 53651119, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Thionyl chloride (1.6 ml) was added to a solution of 2-(4-fluorobenzoyl)benzoic acid (3.6 g) and pyridine (0.03 ml) in benzene (40 ml), followed by refluxing for an hour. The solvent was distilled off to give 2-(4-fluorobenzoyl) benzoyl chloride (IRνmaxNujol : 1790 cm-1).

Workup

  1. temperatureby refluxing for an hour
  2. distillationThe solvent was distilled off

Sources & evidence

ORD record
ord-433461696124480d9c4ea940407c06af
Source dataset
uspto-grants-1993_02
Patent number
US05189043

Reaction notes

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