Hydrochloric Acid → HCID 67857936, compound

Participants

Reaction Steps

To a rapidly stirred solution of 400 mg (0.77 mmol) of 3-amino-4-oxo-4-[([1-(1-oxotridecyl)-2-piperidinyl]methyl)amino]butanoic acid phenylmethyl ester in 6.0 mL of diethyl ether was added 1.5 mL (1.5 mmol) of 1.0N HCl in diethyl ether. The mixture was stirred for 3 minutes and then the resulting solid was collected by vacuum filtration, providing 370 mg (87%) of 3-amino-4-oxo-4-[([1-(1-oxotridecyl)-2-piperidinyl]methyl)amino]butanoic acid phenylmethyl ester hydrochloride as a yellow solid. Mp.>55° C. (decomposition).

Provenance & Evidence