HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acrylate → N-[1-(ethoxycarbonylethyl)-piperid-4-yl]-N-methylpropionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | N-Methyl-N-(piperidin-4-yl)propionamide | HCID 19761222 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-[1-(ethoxycarbonylethyl)-piperid-4-yl]-N-methylpropionamide | HCID 19761283 | — |
Reaction Steps
14 g of ethyl acrylate in 45 ml of ethanol are added dropwise to 23.8 g of the amine obtained in Stage C of Example 1 dissolved in 45 ml of ethanol. The mixture is stirred at room temperature for 3 hours, evaporated, and the residual oil is distilled in a Kugelrohr (bulb tube) at 120° C. and 0.09 mg Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05189045 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-b70e6d78ea6046bbb08cd017da67c6e3 |
| Source note | uspto-grants-1993_02 |