HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1-[4-(Methylamino)piperidin-1-yl]ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | N-Acetyl-4-piperidone | HCID 122563 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-[4-(Methylamino)piperidin-1-yl]ethan-1-one | HCID 19761265 | — |
Reaction Steps
9.9 g of methylamine in 50 ml of ethanol are added to 14.4 g of 1-acetyl-4-oxopiperidine in 100 ml of ethanol. The mixture is then hydrogenated in the presence of platinum oxide at room temperature and atmospheric pressure, filtered and evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05189045 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-d403338957fe41e2b26a0fbe34918afc |
| Source note | uspto-grants-1993_02 |