反应详情

A mixture containing 0.5 mol of the compound obtained in Stage A of Example 19, 0.5 M benzyl chloride and 1 M sodium carbonate in 650 ml of ethanol is refluxed for one night. The precipitate formed is filtered off, the solvent is evaporated, the evaporation residue is taken up in 1N hydrochloric acid and extracted with diethyl ether, and the ethereal extract is rendered basic with sodium hydroxide solution and extracted with ethyl acetate to obtain the desired compound.

1. temperatureis refluxed for one night
2. customThe precipitate formed
3. filtrationis filtered off
4. customthe solvent is evaporated
5. extractionextracted with diethyl ether
6. extractionthe ethereal extract
7. extractionextracted with ethyl acetate