HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 10319531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | HCID 15043966 | HCID 15043966 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 10319531 | HCID 10319531 | 63% |
Reaction Steps
Mix 3-amino-2-carbethoxy-4,6-dichloroindole (3.31 g, and anhydrous pyridine (50 mL). Add, by dropwise addition, phenylsulfonyl chloride (2.35 g, 13.33 mmol). Stir for 48 hours at room temperature. Pour into 1N hydrochloric acid (500 mL), extract with ethyl acetate and dry (MgSO4). Evaporate the solvent in vacuo and recrystallize (ethyl acetate/hexane) to give the title compound (3.15 g, 63%); mp 245°-7° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05189054 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-3581da4bf1a64f868c2f0c8a6d354408 |
| Source note | uspto-grants-1993_02 |