Hydrochloric Acid → 2-Methoxy-benzamidine hydrochloride

HRID 2082721Notes

Reaction equation

[ClH:1].[CH2:2]([O:5][C:6]1[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=1[C:8]([NH2:10])=[NH:9])CC.Cl.COC1C=CC=CC=1C(N)=O>>[ClH:1].[CH3:2][O:5][C:6]1[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=1[C:8]([NH2:10])=[NH:9]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 755402-Methoxybenzamide

HCID 122542252-Propyloxybenzamidine Hydrochloride

Product 1

HCID 122542242-Methoxy-benzamidine hydrochloride

Procedure

In a manner similar to that described for the preparation of 2-n-propoxybenzamidine hydrochloride in Preparation 7, 2-methoxybenzamindine hydrochloride, m.p. 150°-152° was prepared from 2-methoxybenzamide.

Sources & evidence

ORD record: ord-8558f9e37ef24269ba16e7eb99c819bc
Source dataset: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04082751

Reaction notes

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