Phenethylamine → HCID 20360793, compound

HRID 2082814Notes

Reaction equation

HRID 2082814 reaction equation
[O:1]1[CH2:18][CH:2]1[CH2:3][O:4][C:5]1[CH:6]=[C:7]([C:11]2[CH2:12][CH2:13][C:14](=[O:17])[NH:15][N:16]=2)[CH:8]=[CH:9][CH:10]=1.[C:19]1([CH2:25][CH2:26][NH2:27])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[OH:1][CH:2]([CH2:18][NH:27][CH2:26][CH2:25][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH2:3][O:4][C:5]1[CH:6]=[C:7]([C:11]2[CH2:12][CH2:13][C:14](=[O:17])[NH:15][N:16]=2)[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 1001PhenethylamineHCID 20360753HCID 20360753, compound

Product 1

HCID 20360793HCID 20360793, compound

Procedure

6-[3-(2,3-Epoxypropoxy)phenyl]-4,5-dihydro-3(2H)-pyridazinone was reacted with phenylethylamine in a similar manner to that described in Example 1(ii) to give 6-[3-(2-hydroxy-3-phenethylaminopropoxy)phenyl]-4,5-dihydro-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-2db59390c85b4c30b00690324cda68e9
Source dataset
uspto-grants-1978_04
Patent number
US04082843

Reaction notes

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