Hydrazine hydrate (1:1) → HCID 20360770, compound

HRID 2082827Notes

Reaction equation

HRID 2082827 reaction equation
[C:1]([C:3]1[CH:15]=[CH:14][C:6]([C:7]([CH2:9][CH2:10][C:11](O)=[O:12])=O)=[CH:5][C:4]=1[OH:16])#[N:2].O.[NH2:18][NH2:19]>>[C:1]([C:3]1[CH:15]=[CH:14][C:6]([C:7]2[CH2:9][CH2:10][C:11](=[O:12])[NH:18][N:19]=2)=[CH:5][C:4]=1[OH:16])#[N:2]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20360782HCID 20360782, compound

Product 1

HCID 20360770HCID 20360770, compound

Procedure

3-(4-Cyano-3-hydroxybenzoyl)propionic acid was cyclised with hydrazine hydrate in a similar manner to that described in Example 3 (i) to give 6-(4-cyano-3-hydroxyphenyl)-4,5-dihydro-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-d67243763cf1438bac7f8343f7ad6976
Source dataset
uspto-grants-1978_04
Patent number
US04082843

Reaction notes

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