Hydrazine hydrate (1:1) → HCID 20360784, compound

HRID 2082836Notes

Reaction equation

HRID 2082836 reaction equation
[OH:1][C:2]1[C:3]([O:15][CH3:16])=[C:4]([CH:12]=[CH:13][CH:14]=1)[C:5]([CH2:7][CH2:8][C:9](O)=[O:10])=O.O.[NH2:18][NH2:19]>>[OH:1][C:2]1[C:3]([O:15][CH3:16])=[C:4]([C:5]2[CH2:7][CH2:8][C:9](=[O:10])[NH:18][N:19]=2)[CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20360759HCID 20360759, compound

Product 1

HCID 20360784HCID 20360784, compound

Procedure

3-(3-hydroxy-2-methoxybenzoyl)propionic acid was cyclised with hydrazine hydrate in a similar manner to that described in Example 3 (i) to give 6-(3-hydroxy-2-methoxyphenyl)-4,5-dihydro-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-f4eb43c4e4a1460fb843a0cc8d137bbd
Source dataset
uspto-grants-1978_04
Patent number
US04082843

Reaction notes

Loading…