Hydrazine hydrate (1:1) → HCID 20360742, compound

HRID 2082841Notes

Reaction equation

HRID 2082841 reaction equation
[Cl:1][C:2]1[C:14]([OH:15])=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([CH2:6][CH2:7][C:8](O)=[O:9])=O.O.[NH2:17][NH2:18]>>[Cl:1][C:2]1[C:14]([OH:15])=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]1[CH2:6][CH2:7][C:8](=[O:9])[NH:17][N:18]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20360729HCID 20360729, compound

Product 1

HCID 20360742HCID 20360742, compound

Procedure

3-(2-chloro-3-hydroxybenzoyl)propionic acid was cyclised with hydrazine hydrate in a similar manner to that described in Example 3(i) to give 6-(2-chloro-3-hydroxyphenyl)-4,5-dihydro-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-662cebff92b74e4d80639e7e54586a2c
Source dataset
uspto-grants-1978_04
Patent number
US04082843

Reaction notes

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