Isopropanol → Isopropyl 2-(11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate

HRID 2082845Notes

Reaction equation

[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][C:18]([OH:20])=[O:19])=[CH:16][C:3]1=2.[CH3:21][CH:22](O)[CH3:23]>>[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][C:18]([O:20][CH:22]([CH3:23])[CH3:21])=[O:19])=[CH:16][C:3]1=2

Participants

Reactant 2

HCID 3776Isopropanol

HCID 41448Isoxepac

Product 1

HCID 12330026Isopropyl 2-(11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate

Procedure

Reaction of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid, Example 2, with 2-propanol as described in Example 3 provides isopropyl 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetate as colorless crystals, mp 67°-68.5° C.

Sources & evidence

ORD record: ord-a938a77ae0064399a7c9cea7abf2be12
Source dataset: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04082850

Reaction notes

Loading…