1-Dodecanol → HCID 178443312, compound
Reaction equation
[CH3:1][O:2][P:3]([O-:5])[O-:4].[CH2:6]([Sn+2:10]([CH2:15][CH2:16][CH2:17][CH3:18])[CH2:11][CH2:12][CH2:13][CH3:14])[CH2:7][CH2:8][CH3:9].[CH2:19](O)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]C>>[CH2:1]([O:2][P:3]([O-:5])[O-:4])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH3:19].[CH2:15]([Sn+2:10]([CH2:6][CH2:7][CH2:8][CH3:9])[CH2:11][CH2:12][CH2:13][CH3:14])[CH2:16][CH2:17][CH3:18]Participants
Conditions
- Temperature
- 140 °C
Procedure
In a 500 ml four-neck round-bottom flask, as described in Example 1, 148.85 g of tributyltin oxide and 110 g dimethyl phosphite are heated with stirring to about 120° C. The reaction mixture is kept at this temperature for about 2 hours, dimethyl ether being split off. The reaction mixture is then heated with stirring under a vacuum of 20 to 5 mm Hg at 145° C, until the excess dimethyl phosphite has been distilled off. 193.3 g of tributyltin methyl phosphite are obtained. 128.5 g of tributyltin methyl phosphite and 68.7 g of lauryl alcohol are heated with stirring in a 500 ml four-neck round-bottom flask equipped with a stirrer, thermometer, standard taper glass stopper, stillhead with condenser, cooled distillate receiver and cold trap at 140° C for 5 hours, for one hour of which a vacuum (30 - 5 mm HG) is applied. Methanol is distilled off. 178 g tributyltin lauryl phosphite are obtained.
Workup
- customequipped with a stirrer
- distillationMethanol is distilled off
Sources & evidence
- ORD record
- ord-630b235141c6429296fadad94e1a144d
- Source dataset
- uspto-grants-1978_04
- Patent number
- US04083860
Reaction notes
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