(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → Mannitol

HRID 2082972Notes

Reaction equation

HRID 2082972 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].O=C[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>>[CH2:11]([OH:12])[C@H:9]([C@H:7]([C@@H:5]([C@@H:3]([CH2:2][OH:1])[OH:4])[OH:6])[OH:8])[OH:10]

Participants

3

Reactant 2

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 161658Demannose

Product 1

HCID 6251Mannitol

Procedure

Thus, the mixture of D-glucose and D-mannose obtained in the above is subjected to the catalytic hydrogenation, thereby is formed D-mannitol at a high ratio such as 30-36% based on the initial D-glucose, which results in such a high yield of crystalline D-mannitol as 25-30%.

Workup

  1. customobtained in the

Sources & evidence

ORD record
ord-a77b808f309b43d1a39d19490fc392cd
Source dataset
uspto-grants-1978_04
Patent number
US04083881

Reaction notes

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