Sodium hydride → HCID 54182312, compound

HRID 2083008Notes

Reaction equation

HRID 2083008 reaction equation
[H-].[Na+].[CH:3](=[C:10]1[CH2:15][CH2:14][CH2:13][CH2:12][C:11]1=[N:16][OH:17])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:18][CH:19]([CH2:22][N:23]1[CH2:28][CH2:27][N:26]([CH3:29])[CH2:25][CH2:24]1)[CH2:20]Cl>>[CH:3](=[C:10]1[CH2:15][CH2:14][CH2:13][CH2:12][C:11]1=[N:16][O:17][CH2:18][CH:19]([CH3:20])[CH2:22][N:23]1[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 3

HCID 24758Sodium hydrideHCID 189199HCID 189199, compoundHCID 224032101-(3-Chloro-2-methylpropyl)-4-methylpiperazine

Product 1

HCID 54182312HCID 54182312, compound

Procedure

On starting from 2.4 g (0.1 moles) of sodium hydride, 20.1 g (0.1 moles) of 2-benzalcyclohexanone oxime and 20.76 g (0.11 moles) of 2-methyl-3-(4'-methylpiperazinyl)-propyl chloride, one proceeds in the way specified in Example 1.

Sources & evidence

ORD record
ord-e0059d26fe354c8aaa61ef8f1faf4962
Source dataset
uspto-grants-1978_04
Patent number
US04083978

Reaction notes

Loading…