2-Chlorothiazole → HCID 85907747, compound

Participants

Reaction Conditions

Reaction Steps

A mixture consisting of 2.4 gm of 2-chloro-thiazole and 5.6 gm of ethyl 4-amino-isophthalate was heated for eight hours at 150° C on an oil bath. Thereafter, the resulting dark brown oil was refluxed with 10 ml of acetonitrile for one hour, the reaction mixture was then thoroughly cooled, and the crystals formed thereby were collected by suction filtration and recrystallized from a little methanol. The compound of the formula ##STR9##

Provenance & Evidence