Hydrochloric Acid → HCID 85907803, compound

Participants

Reaction Steps

2.8 gm of ethyl 12-oxo-12-H-quino[2,1-b]quinazoline-10-carboxylate (see Example 3) were refluxed in 20 ml of an aqueous 10% sodium hydroxide solution for 30 minutes. The solution was then heated with 5 times its quantity of semiconcentrated hydrochloric acid for half an hour on a boiling water bath. After diluting with water, the precipitated yellow crystals were collected by suction filtration and washed with water and acetonitrile, yielding the compound of the formula ##STR26##

Provenance & Evidence