Phosphorus trichloride → HCID 21313167, compound

HRID 2083077Notes

Reaction equation

HRID 2083077 reaction equation
[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[N:6][C:5]([C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:4][N+:3]=1[O-].P(Cl)(Cl)Cl>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[N:6][C:5]([C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 24387Phosphorus trichlorideHCID 178441362HCID 178441362, compound

Product 1

HCID 21313167HCID 21313167, compound

Procedure

The pyrazine 1-oxide obtained above was then allowed to react with phosphorus trichloride to yield 2-amino-3-cyano-5-t-butylpyrazine, which was in turn hydrolyzed and decarboxylated to yield 2-amino-5-(t-butyl)pyrazine, identified by IR spectrum.

Sources & evidence

ORD record
ord-8f0f46289f1242cfa35843dc54d7ea3c
Source dataset
uspto-grants-1978_04
Patent number
US04083977

Reaction notes

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