Acetoacetic Acid → L-Glutamic Acid

HRID 2083087Notes

Reaction equation

HRID 2083087 reaction equation
N[C@H:2]([C:10]([OH:12])=[O:11])CC1C=CC=CC=1.[NH2:13][C@H:14]([C:16]([OH:18])=[O:17])[CH3:15].N[C@H](C(O)=O)CC1C=CC(O)=CC=1.NCC(O)=O.N[C@H](C(O)=O)CCCNC(=N)N.CC(CC(O)=O)=O>>[NH2:13][C@H:14]([C:16]([OH:18])=[O:17])[CH2:15][CH2:2][C:10](=[O:11])[OH:12]

Participants

7

Reactant 6

HCID 96Acetoacetic AcidHCID 750GlycineHCID 5950L-AlanineHCID 6057L-TyrosineHCID 6140L-PhenylalanineHCID 178418600HCID 178418600, compound

Product 1

HCID 33032L-Glutamic Acid

Procedure

1.03 His: 0.97 Phe: 2.00 Ala: 0.95 Tyr: 1.04 Gly: 0.97 Arg: 0.94 Pro: 0.96 Recovery: 85% (calculated as the diacetate).

Sources & evidence

ORD record
ord-5cb1dd2ccec5433c8f5fc9170b108a88
Source dataset
uspto-grants-1978_04
Patent number
US04083967

Reaction notes

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