Acetoacetic Acid → L-Glutamic Acid

HRID 2083089Notes

Reaction equation

HRID 2083089 reaction equation
N[C@H:2]([C:11]([OH:13])=[O:12])CC1C=CC(O)=CC=1.[NH2:14][C@H:15]([C:17]([OH:19])=[O:18])[CH3:16].N[C@H](C(O)=O)CC1C=CC=CC=1.NCC(O)=O.N[C@H](C(O)=O)CC(C)C.N[C@H](C(O)=O)CCCNC(=N)N.CC(CC(O)=O)=O>>[NH2:14][C@H:15]([C:17]([OH:19])=[O:18])[CH2:16][CH2:2][C:11](=[O:12])[OH:13]

Participants

8

Reactant 7

HCID 96Acetoacetic AcidHCID 750GlycineHCID 5950L-AlanineHCID 6057L-TyrosineHCID 6106L-LeucineHCID 6140L-PhenylalanineHCID 178418600HCID 178418600, compound

Product 1

HCID 33032L-Glutamic Acid

Procedure

1.05 His: 1.03 Tyr: 0.99 Ala: 1.02 Phe: 1.00 Gly: 1.07 Leu: 1.00 Arg: 0.94 Pro: 1.02 Recovery 95% (calculated as the diacetate)

Sources & evidence

ORD record
ord-57b9c441efda4abfbf3c5216c5b2602d
Source dataset
uspto-grants-1978_04
Patent number
US04083967

Reaction notes

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