Benzene → HCID 20322125, compound

HRID 2083100Notes

Reaction equation

HRID 2083100 reaction equation
C([O:3][C:4](=[O:18])[CH:5]([CH2:11][CH2:12][CH:13]([CH3:17])[CH2:14][CH2:15][Br:16])C(OCC)=O)C.Br.C1C=CC=CC=1>O>[Br:16][CH2:15][CH2:14][CH:13]([CH3:17])[CH2:12][CH2:11][CH2:5][C:4]([OH:18])=[O:3]

Participants

5

Reactant 3

HCID 241BenzeneHCID 260Hydrogen Bromide2×HCID 54445285HCID 54445285, compound

Product 1

HCID 20322125HCID 20322125, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

30 g of (5-bromo-3-methylpentyl)-malonic acid diethyl ester were heated to the boil, while stirring, with 15 ml of 48% HBr and 15 ml of HBr/glacial acetic acid, whereby the low-boiling products were distilled off. After 7 hours the cooled reaction solution was distributed between benzene and water and the organic phase was evaporated with MgSO4 after drying and distilled off. Boiling point1 : 119° - 121° C

Workup

  1. distillationwere distilled off
  2. customAfter 7 hours the cooled reaction solution
  3. customthe organic phase was evaporated with MgSO4
  4. customafter drying
  5. distillationdistilled off
  6. custom119° - 121° C

Sources & evidence

ORD record
ord-2beb4bde54dc44fd8a05d3a53d9ad68b
Source dataset
uspto-grants-1978_04
Patent number
US04083990

Reaction notes

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