Hydrochloric Acid → HCID 178466054, compound

HRID 2083232Notes

Reaction equation

HRID 2083232 reaction equation
C([O:4][CH:5]([C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[O:13][CH:12]=[C:11]([C:17]1[NH:21][N:20]=[N:19][N:18]=1)[C:10]2=[O:22])[CH3:6])(=O)C.[OH-].[Na+].Cl>>[OH:4][CH:5]([C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[O:13][CH:12]=[C:11]([C:17]1[NH:21][N:20]=[N:19][N:18]=1)[C:10]2=[O:22])[CH3:6]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 178476189HCID 178476189, compound

Product 1

HCID 178466054HCID 178466054, compound

Procedure

A solution of 0.300 part of 6-(1-acetoxyethyl)-3-(1H-tetrazol-5-yl)chromone in 4 parts by volume of 1N-NaOH is stirred at room temperature for 1 hour and then acidified with 1N-hydrochloric acid. The resulting precipitates are recovered by filtration and recrystallized from ethanol to obtain 0.100 of 6-(1-hydroxyethyl)-3-(1H-tetrazol-5-yl)chromone as colorless crystals melting at 234°-236° C (decomposition with foaming).

Workup

  1. customThe resulting precipitates
  2. filtrationare recovered by filtration
  3. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-e6826edde3c74369ad766ec0e822014f
Source dataset
uspto-grants-1978_04
Patent number
US04085116

Reaction notes

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