Sodium borohydride → HCID 178466054, compound

Participants

Reaction Steps

To a suspension of 0.128 part of 6-acetyl-3-(1H-tetrazol-5-yl)chromone in 5 parts by volume of methanol is added under stirring 0.020 part of sodium borohydride. The resulting mixture is stirred at room temperature for 2 minutes and then refluxed for 2 minutes. The solvent is distilled off and to the residue is added 10 parts by volume of 1N-hydrochloric acid. The resulting precipitates are recovered by filtration and recrystallized twice from ethanol to obtain 0.013 part of 6-(1-hydroxyethyl)-3-(1H-tetrazol-5-yl)chromone as colorless crystals melting at 234°-236° C(decomposition with foaming).

Provenance & Evidence