Phenol → Phenyl chloroformate

HRID 2083262Notes

Reaction equation

HRID 2083262 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:8](Cl)([Cl:10])=[O:9]>CN(C)C=O>[C:1]1([O:7][C:8]([Cl:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 996PhenolHCID 6371Phosgene

Product 1

HCID 15891Phenyl chloroformate

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a device provided with a deep-freezing cooler as described in Example 1 a mixture of 94 g of phenol and 15 g of N,N-dimethyl-formamide was reacted at 80° C within 3 hours with 150 g of phosgene. After the reaction had been completed, the mixture was distilled. About 110g of chloroformic acid phenyl ester were obtained. In the distillation flask, a strongly hygroscopic residue remained wich served as catalyst for the following reaction.

Workup

  1. customIn a device provided with a deep-freezing cooler
  2. distillationthe mixture was distilled

Sources & evidence

ORD record
ord-bfe438a4a2f34cc8b1f9575331c0e070
Source dataset
uspto-grants-1978_04
Patent number
US04085129

Reaction notes

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