HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2,2-diphenylbutyronitrile → 1-(3,3-Diphenylpropyl)piperidine--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2,2-diphenylbutyronitrile | HCID 96575 | — |
| Reactant | 1,1'-(3-Chloropropane-1,1-diyl)dibenzene | HCID 190135 | — |
| Reactant | Piperidine, hydrochloride (1:1) | HCID 2723721 | — |
| Product | 1-(3,3-Diphenylpropyl)piperidine--hydrogen chloride (1/1) | HCID 197784 | — |
Reaction Steps
Repetition of the procedure detailed in Example 12 using piperidine hydrochloride and 1,1-diphenyl-3-chloropropane in place of the 2-azabicyclo[2.2.2]octane hydrochloride and 2,2-diphenyl-4-bromobutyronitrile affords 1-(3,3-diphenylpropyl)piperidine hydrocloride, melting at about 216° - 217° C., and represented by the following structural formula. ##STR13##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04086234 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-7ffe07cbf4da48a9af488daf9fb5825e |
| Source note | uspto-grants-1978_04 |