Potassium Hydroxide → HCID 88813360, compound

HRID 2083730Notes

Reaction equation

HRID 2083730 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[N:16][OH:17])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]#[N:15])=[CH:4][CH:3]=1.Cl.Cl[CH2:20][CH2:21][NH2:22].[OH-].[K+]>CN(C)C=O>[ClH:1].[NH2:22][CH2:21][CH2:20][O:17][N:16]=[C:8]([C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]#[N:15]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 97937372-Chloroethylamine hydrochlorideHCID 88813015HCID 88813015, compound

Product 1

HCID 88813360HCID 88813360, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
10 °C

Procedure

5.0 mmol. (1.25 gr) of 4'-chloro-6-cyanocaprophenone oxime, melting point 58°-59° C, 5.2 mmol (0.60 gr) of 2-chloroethylaminehydrochloride and 0.7 gr of KOH powder were sequentially added to 12.5 ml of dimethyl-formamide (DMF) while stirring at 10° C.

Sources & evidence

ORD record
ord-f53fe93e314e474ab016f2b5d39be0d1
Source dataset
uspto-grants-1978_04
Patent number
US04086361

Reaction notes

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