Ethylene Oxide → HCID 13319428, compound

Participants

Reaction Steps

To a solution of 13.2 g. (0.0318 m.) of 4-(2-chloro-9-thioxanthenylidene)-piperidine in 50 ml. of methanol at 50° C. is added a solution of 2.2 g. (0.0383 m.) of ethylene oxide in 30 ml. of methanol over ten minutes and the mixture is refluxed for one and one-half hours. After standing overnight at room temperature, the reaction mixture is filtered to yield 4-(2-chloro-9-thioxanthenylidene)-1-(β-hydroxyethyl)-piperidine, m.p. 178°-180° C.

Provenance & Evidence