HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionic Acid → HCID 20357522, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionic Acid | HCID 1032 | — |
| Reactant | Sulphobenzoic anhydride | HCID 13795534 | — |
| Reactant | 6-Chloro-2-fluoro-9-(1-methylpiperidin-4-yl)-9H-thioxanthen-9-ol | HCID 20357482 | — |
| Product | HCID 20357522 | HCID 20357522 | — |
Reaction Steps
Dehydration is accomplished by heating 6.4 g. (0.018 mol) of the above thioxanthene-9-ol for one hour with 6.5 g. (0.035 mol) of o-sulfobenzoic anhydride in 100 ml. of propionic acid. Workup the reaction mixture affords 4-(6-chloro-2-fluoro-9-thioxanthenylidene) 1-methylpiperidine, isolated as the hydrochloride salt, m.p. 264°-265° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04086350 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-bc2a7b0e4c5a42bb903593d02bc63262 |
| Source note | uspto-grants-1978_04 |