反应详情

Aqueous sodium hydroxide (10 ml of a 2.5 N solution) is added dropwise over 15 minutes to a stirring solution of methyl N-(p-nitrobenzyloxycarbonyl)-α-methoxyglycinate (7.46 g, 25 mMol) in methanol (5 ml). The methanol is removed under reduced pressure and the aqueous residue is lyophilized to give sodium N-(p-nitrobenzyloxycarbonyl)-α-methoxyglycinate.

1. customThe methanol is removed under reduced pressure