Sodium Hydroxide → HCID 20357868, compound

HRID 2083803Notes

Reaction equation

HRID 2083803 reaction equation
[OH-].[Na+:2].[N+:3]([C:6]1[CH:23]=[CH:22][C:9]([CH2:10][O:11][C:12]([NH:14][CH:15]([O:20][CH3:21])[C:16]([O:18]C)=[O:17])=[O:13])=[CH:8][CH:7]=1)([O-:5])=[O:4]>CO>[N+:3]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][O:11][C:12]([NH:14][CH:15]([O:20][CH3:21])[C:16]([O-:18])=[O:17])=[O:13])=[CH:22][CH:23]=1)([O-:5])=[O:4].[Na+:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 20357887methyl N-(p-nitrobenzyloxycarbonyl)-alpha-methoxyglycinate

Product 1

HCID 20357868HCID 20357868, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Aqueous sodium hydroxide (10 ml of a 2.5 N solution) is added dropwise over 15 minutes to a stirring solution of methyl N-(p-nitrobenzyloxycarbonyl)-α-methoxyglycinate (7.46 g, 25 mMol) in methanol (5 ml). The methanol is removed under reduced pressure and the aqueous residue is lyophilized to give sodium N-(p-nitrobenzyloxycarbonyl)-α-methoxyglycinate.

Workup

  1. customThe methanol is removed under reduced pressure

Sources & evidence

ORD record
ord-3ce6ec277ffa44f997e91fda260ba89e
Source dataset
uspto-grants-1978_04
Patent number
US04086423

Reaction notes

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