Hydrochloric Acid → HCID 178446014, compound

Participants

Reaction Steps

A solution of 1.69 g. of Nα -t-butoxycarbonyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl-glycinamide hydrochloride in 20 ml. of methanol and 10 ml. of 3N hydrogen chloride in 10 ml. of tetrahydrofuran is allowed to stand for 1 hour and then evaporated to dryness at 30° C. under reduced pressure. The residue is twice dissolved in 20 ml. of methanol and the solvent evaporated. It is then dried at 45° C. under reduced pressure. The product is used without further purification.

Provenance & Evidence