Water → HCID 13008380, compound

HRID 2083847Notes

Reaction equation

HRID 2083847 reaction equation
[Br:1][C:2]1[C:6]([N+:7]([O-:9])=[O:8])=[C:5](Br)[N:4]([CH2:11][CH2:12][CH2:13][N:14]2[C:18](Br)=[C:17]([N+:20]([O-:22])=[O:21])[C:16]([Br:23])=[N:15]2)[N:3]=1.[CH2:24]([NH2:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1.O>C(O)CC>[CH2:24]([NH:31][C:18]1[N:14]([CH2:13][CH2:12][CH2:11][N:4]2[C:5]([NH:31][CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[C:6]([N+:7]([O-:9])=[O:8])[C:2]([Br:1])=[N:3]2)[N:15]=[C:16]([Br:23])[C:17]=1[N+:20]([O-:22])=[O:21])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

5

Reactant 3

HCID 962WaterHCID 7504BenzylamineHCID 13008379HCID 13008379, compound

Product 1

HCID 13008380HCID 13008380, compound

Reagents, catalysts & solvents 1

HCID 10311-PropanolSolvent

Procedure

11.6 g of 1,3-bis-(3,5-dibromo-4-nitropyrazol-1-yl)propane from step 5.1 are heated together with 6.5 g of benzylamine in 180 ml of n-propanol for 1 hour at 100° C. Subsequently the reaction mixture is cooled and poured into 1000 ml water. The precipitate is filtered with suction, washed with water and dried in vacuum at 60° C.

Workup

  1. temperatureSubsequently the reaction mixture is cooled
  2. filtrationThe precipitate is filtered with suction
  3. washwashed with water
  4. customdried in vacuum at 60° C.

Sources & evidence

ORD record
ord-6d7cbff24ef646f0b39abe930569f5e2
Source dataset
uspto-grants-2004_04
Patent number
US06716257B2

Reaction notes

Loading…