Daidzein → Equol

HRID 2083852Notes

Reaction equation

HRID 2083852 reaction equation
[CH:1]1[C:6]([C:7]2[C:16](=O)[C:15]3[CH:14]=[CH:13][C:12]([OH:18])=[CH:11][C:10]=3[O:9][CH:8]=2)=[CH:5][CH:4]=[C:3]([OH:19])[CH:2]=1>O>[CH:5]1[C:6]([C@H:7]2[CH2:8][O:9][C:10]3[CH:11]=[C:12]([OH:18])[CH:13]=[CH:14][C:15]=3[CH2:16]2)=[CH:1][CH:2]=[C:3]([OH:19])[CH:4]=1

Participants

3

Reactant 1

HCID 5281708Daidzein

Product 1

HCID 91469Equol

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Using a substrate solution containing 0.01 mg/ml of daidzein (manufactured by Funakoshi, purity ≧99%) (5 mg of daidzein suspended in 2 ml of special grade methanol and diluted to 50 ml with BHI (brain heart infusion) medium) in lieu of the above water-soluble soya isoflavone material, equol was produced in otherwise the same manner as above. As a result, the amount of equol in the fermentation broth after 96 hours of culture was 17.9±1.4 μg/ml (mean of 5 determinations ±S.D.).

Sources & evidence

ORD record
ord-a15f7ad7497a4de3b0342e5c17c36c32
Source dataset
uspto-grants-2004_04
Patent number
US06716424B1

Reaction notes

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