Pyrrolidine → HCID 178461085, compound

HRID 2083951Notes

Reaction equation

HRID 2083951 reaction equation
C(OC([NH:11][C@H:12]([C:20]([OH:22])=O)[CH2:13][CH2:14][CH2:15][NH:16][C:17](=[NH:19])[NH2:18])=O)C1C=CC=CC=1.[CH2:23]([S:26]([Cl:29])(=[O:28])=[O:27])[CH2:24][CH3:25].[NH:30]1[CH2:34][CH2:33][CH2:32][CH2:31]1>>[ClH:29].[NH:19]=[C:17]([NH:18][S:26]([CH2:23][CH2:24][CH3:25])(=[O:28])=[O:27])[NH:16][CH2:15][CH2:14][CH2:13][C@@H:12]([C:20]([N:30]1[CH2:34][CH2:33][CH2:32][CH2:31]1)=[O:22])[NH2:11]

Participants

4

Reactant 3

HCID 31268PyrrolidineHCID 662791-Propanesulfonyl chlorideHCID 178512917HCID 178512917, compound

Product 1

HCID 178461085HCID 178461085, compound

Procedure

Starting from (S)-N2-(benzyloxycarbonyl)-arginine, propanesulphonyl chloride and pyrrolidine, the expected product is obtained according to the procedure described in Example 1.

Sources & evidence

ORD record
ord-e98382615813485fb1ab1f036a02fe98
Source dataset
uspto-grants-2004_04
Patent number
US06716843B2

Reaction notes

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