HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 22732060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-(1H-Indol-6-yl)ethan-1-ol | HCID 12991240 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22732060 | HCID 22732060 | 106.5% |
Reaction Steps
6-(2-Hydroxyethyl)-indole (72.5 mg, 0.45 mmol) was mixed with Et3N (126 mg, 1.35 mmol) in 2 ml of dichloromethane at 0 to 5° C. Methane sulfonyl chloride (61.6 mg, 0.54 mmol) was added and the mixture stirred for 1 hr, diluted with dichloromethane, washed with brine, dried and concentrated to give 107 mg of the title compound (quantitative yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716837B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-041dfc14ef0b45c9b29c15133c69cd66 |
| Source note | uspto-grants-2004_04 |